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Molecular and Cellular Exercise Physiology

Molecular and Cellular Exercise Physiology

$159.95 CAD

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    With Molecular and Cellular Exercise Physiology, you’ll gain cutting-edge information on how exercise modulates cellular physiology. You’ll be able to use that knowledge to develop better training regimens and injury-prevention and rehabilitation programs. You’ll also be able to improve performance. The book is unique in that it is the first comprehensive text to address the effects of physical activity on the cellular and molecular level.

    Molecular and Cellular Exercise Physiology highlights the potential of physical training in the prevention and treatment of chronic diseases while thoroughly exploring these topics:

    • Fundamental cellular and molecular mechanisms responsible for changes in stroke volume, blood gas homeostasis, pH alterations, blood pressure, and osmosis in response to exercise
    • How the exercise effects are mediated and translated into specific cellular and subcellular alterations

    Recent fascinating advances in molecular techniques have extended the field of exercise physiology and enabled researchers to address the mechanisms involved on a subcellular and molecular level. Molecular and Cellular Exercise Physiology is a vital reference to help you stay on top of this exciting field.

    Table of Contents

    Part I: Molecular Exercise Physiology
    Chapter 1.
    The Cell
    • Cellular Architecture
    • Exercise and the Cell
    • Conclusion

    Chapter 2. Cellular Life Span
    • Cell Cycle and Tissue Turnover
    • Cell Death
    • Effect of Exercise on Cell Proliferation and Cell Death
    • Conclusion

    Chapter 3. Genes, Genetic Heterogeneity, and Exercise Phenotypes
    • Genes and Genome
    • Gene Expression
    • Regulation of Gene Expression
    • Exercise and Gene Expression
    • DNA Sequence Variation
    • Genetics and Responsiveness to Exercise Training
    • Conclusion

    Chapter 4. Proteins and Exercise
    • Protein Synthesis
    • Protein Degradation
    • Exercise and Protein Metabolism
    • Conclusion

    Chapter 5. Extracellular Matrix and Exercise
    • Extracellular Matrices
    • Composition of the Interstitial Extracellular Matrix
    • Composition of Basement Membranes
    • Synthesis of Collagens
    • Degradation of Collagens
    • ECM of Skeletal Muscle
    • Muscle ECM and Physical Activity

    Chapter 6. Regulation of Intracellular Ion Composition and pH
    • Potassium
    • Intracellular pH Regulation
    • Magnesium

    Chapter 7. Inter- and Intracellular Signaling
    • Hormones and Receptors
    • Intracellular Signal Transduction

    Chapter 8. Energy Turnover and Substrate Utilization
    • Skeletal Muscle Carbohydrate Metabolism During Exercise
    • Recent Advances in the Regulation of Long Chain Fatty Acid Transport and Metabolism
    • Molecular Basis of Lactate Transport in Skeletal Muscle

    Chapter 9. Generation and Disposal of Reactive Oxygen and Nitrogen Species
    • Reactive Oxygen and Nitrogen Species in Living Organisms
    • Reactive Oxygen and Nitrogen Species in Exercise
    • Conclusion

    Chapter 10. Cellular Responses to Environmental Stress
    • Hyperthermia
    • Hypoxia

    Part II: Exercise and the Cell
    Chapter 11.
    Exercise and the Cardiac Myocyte
    • Structure of the Cardiac Myocyte
    • Contractile Cycle and Excitation–Contraction Coupling
    • Adaptive Hypertrophy and Growth Signaling
    • Contractile Function and Calcium Handling

    Chapter 12. Exercise and Endothelium
    • Endothelium Cell Function
    • Effects of Physical Training on Vascular Reactivity
    • Conclusion

    Chapter 13. Activity-Dependent Adaptive Responses of Skeletal Muscle Fibers
    • The Multiplicity of Sarcomeric Protein Isoforms
    • Myofibrillar Protein Isoforms and Fiber Diversity
    • Metabolic Adaptations of Muscle Fibers to Altered Functional Demands
    • Fiber Type Transitions
    • Signaling Pathways Related to Fiber Type Transitions
    • Conclusion

    Chapter 14. Exercise and the Alveolar and Bronchial Epithelial Cell
    • Airways
    • The Alveolar Epithelium

    Chapter 15. Exercise and the Liver Cell
    • Hepatic Carbohydrate Metabolism
    • Hepatic Lipid Metabolism
    • Conclusion

    Chapter 16. Exercise and the Adipocyte
    • The Adipocyte: Characteristics and Functions
    • Adipocyte Receptors and Exercise
    • Conclusion

    Chapter 17. Erythrocytes
    • Red Cell Production
    • Principles of O2 Transport by the Hemoglobin Molecule
    • Principles of CO2 Transport in the Blood
    • Regulation of Red Cell Volume
    • Red Cell Influence on Circulation and Respiration
    • Erythrocyte and Radicals
    • Conclusion

    Chapter 18. Leukocytes
    • Acute Exercise and Leukocytes
    • Mechanisms of Action
    • Chronic Exercise and Leukocyte Subpopulations
    • Exercise and Infections
    • Conclusion

    Chapter 19. Exercise and the Brain
    • Exercise Improves Cognitive Function in Humans and Prevents Age-Related Brain Atrophy
    • Animal Models to Study the Effects of Exercise on Brain Function
    • Exercise Up-Regulates Brain-Derived Neurotrophic Factor
    • Gene Microarray Analysis Reveals Other Genes That Are Regulated by Exercise
    • Exercise Enhancement of Learning and BDNF
    • Exercise and Depression
    • Definitive Role for BDNF in Human Cognition
    • CNS and Peripheral Regulatory Mechanisms of Exercise Effect on BDNF
    • Conclusion